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Noise not just an ISO issue
In general, the amount of noise you'll see at high ISO speeds varies widely depending upon exposure, focus and focus area. For instance, this relatively bright exposure, shot at ISO 2000 (1/40 sec, f/4.5) displays absolutely no noise in the background fabric and a surprisingly saturated (albeit inaccurate) red for Hellboy's face.
Photo credit: Lori Grunin
