Pros + Picture quality is bright, clear and crisp
+ Wireless features are easy to use, and offer some interesting content
+ Excellent build quality
+ User interface is intuitive
+ Performance, even with 1000's of pictures on SD card, is relatively quick.
Cons - Off axis viewing could be better
Summary I have researched these frames ad-nauseam, searching for one that has decent PQ, an AMERICAN user interface (not some poorly translated Chinese junk), and that is relatively Mac-friendly.
With iPhoto '09 and the Flickr support, this frame becomes a no-brainer for the Mac user looking for a very high quality product. (It goes without saying that the PC users are well accommodated as well).
This is the frame to get.